Liquid / syrup Manufacturing plant

Applications & Process :

Pharma FabTM Industries has been designed & manufacturing preparation vessels and has consolidated a process knowledge concerning sterile injectable solution, dispersions, ophthalmic products, syrup and suppositories.

Salient Features :

  • The complete plant is manufactured under current Good Manufacturing Practice (cGMP).
  • All contact parts are made up of SS 316 and non-contact parts from SS 304 .
  • The plant is easy to dismantle, clean and assemble.
  • All vessels are provided with bottom entry stirrer/homogenizer through a specially designed mechanical seal.
  • Bottom entry stirrer/homogenizer leads to less vibration, no coupling in the drive, low maintenance and reduces overall tank height.
  • Top entry stirrer/ homogenizer can also be provided. (OPTIONAL)
  • The plant can be equipped with CIP / SIP facility and Load Cell for online weighing. (OPTIONAL)
  • The plant can be provided with operation through Semi-Automatic/Automatic (PLC) mode.

Preparation Vessels & Tank :

  • Capacity up to 20,000 Litres.
  • Design as per GMP and cGMP
  • Product Contact parts SS 316 / SS 316L and Non Contact Parts SS 304 .
  • Extremely hygienic processing plant.
  • Less manual handling.
  • Atmospheric, Vacuum Pressure Operation.
  • Jacket can be provided for heating & cooling.
  • Vessel Inside Pressure (-1 bar to +2 Bar)
  • Heating Jacket Pressure (-1bar to +6 bar)
  • Heating by steam or hot water circulation.
  • Thermally Insulated.
  • internal surface.Mechanical or Electro polished
  • Welded Flanged or Hinged type LID / Cover
  • Integrated Cleaning in Place-CIP.
  • Sterilizing In Place-SIP as an (Optional)
  • Validation Protocols & Instrumentation calibration.

Variable Speed Agitation :

  • Agitator can be top or bottom driven
  • Propeller type, Anchor type provided with High speed disperser or rotor-stator homogenizer.
  • Single or double mechanical seal.

Fully automatic Liquid Syrup Manufacturing Plant consisting of :

  • Sugar Melting Vessel with mixing stirrer.
  • Basket Filter & Transfer Pump.
  • Syrup Manufacturing Vessel with stirrer.
  • Inline Homogenizer.
  • Zero Hold up Filter press.
  • Storage Tank with stirrer.
  • Interconnecting pipeline.
  • Transfer Pumps.
  • Integrated automatic control panel.
  • Working Platform.

Turn Key Process Line :

  • For production, filtration, transfer and storage solution.
  • Pre reparation vessels.
  • Inline homogenizer.
  • Inter Connecting Pipe
  • Solid or sugar Charging System
  • Working Platform.

Automation available, appropriate for the intended process function, including CIP and SIP :

  • Controls of all function by PLC Controls with HMI Touch screen.
  • Level controls by means of capacitance probe or electronic load cells.
  • Digital indication and controls of all process parameters for Process time, agitator speed, tem perature, pressure & level.